Xofigo® - radium Ra 223 dichloride injection

Important Safety Information

Do not take Xofigo if you are pregnant or may become pregnant. Xofigo can harm your unborn baby. Women who are pregnant or
who may become pregnant should not come in contact with Xofigo without protection, such as gloves. Continue reading below

Dosing & Administration

You will receive treatment with Xofigo® in a clinic or facility where healthcare providers or technicians have been trained to give radiation therapy.

The recommended dosing schedule for Xofigo IV injections is one IV injection every 4 weeks for 6 months (for a total of 6 IV injections). The use of Xofigo beyond 6 injections has not been studied. Each injection will be administered over 1 minute.

Indication

Xofigo® (radium Ra 223 dichloride) injection is used to treat prostate cancer that is resistant to medical or surgical treatments that lower testosterone and has spread to your bones with symptoms, but not to other parts of your body. The medical term for this condition is metastatic castration-resistant prostate cancer, or mCRPC.

Important Safety Information

Do not take Xofigo if you are pregnant or may become pregnant. Xofigo can harm your unborn baby. Women who are pregnant or who may become pregnant should not come in contact with Xofigo without protection, such as gloves.

Before taking Xofigo, tell your healthcare provider if you:

While you are on Xofigo:

The most common side effects of Xofigo include:

Tell your healthcare provider if you have any side effects that bother you or do not go away.

You are encouraged to report negative side effects or quality complaints of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call
1-800-FDA-1088. For important risk and use information about Xofigo, please see the Full Prescribing Information.