THIS SITE IS FOR US AUDIENCES ONLY.

Important Safety Information

Do not take Xofigo® if you are pregnant or may become pregnant. Xofigo can harm your unborn baby. Women who are pregnant... Continue reading below.

THIS SITE IS FOR US AUDIENCES ONLY.

Important Safety Information

Do not take Xofigo® if you are pregnant or may become pregnant. Xofigo can harm your unborn baby. Women who are pregnant or who may become pregnant should not come in contact with Xofigo without protection, such as gloves.
Continue reading below.


Supporting you along the way

It's always important to remember that you are not alone, and that there are other people in the same situation as you who may be able to suggest new ways you can deal with your condition. If you need information, advice, or a place where you can talk to people in a similar situation, these resources may be helpful.

CANCERCARE®

1-800-813-HOPE
(1-800-813-4673)

CancerCare is the leading US-based organization providing professional support services and information to help people manage the emotional, practical, and financial challenges of cancer. CancerCare services are provided by professional oncology social workers and are completely free of charge.

Cancer Support Community

1-888-793-9355

The Cancer Support Community is a strong voice for the patient experience. Its mission is to ensure that all people impacted by cancer are empowered by knowledge, strengthened by action, and sustained by community. Every person impacted by cancer has a unique story and experience to share. The Cancer Experience Registry is a place where the individual and the collective voices of patients, survivors, and caregivers can be heard.

Malecare

1-212-673-4920

Malecare is America’s leading men’s cancer survivor support and advocacy national nonprofit organization. They are known for their men’s health programs for underserved populations, like African American, LGBT, and Native American cancer survivors. All of their services are provided without cost to the patient and their families.

Men’s Health Network

1-202-543-MHN-1
(1-202-543-6461)

Men’s Health Network (MHN) is a national nonprofit organization whose mission is to reach men, boys, and their families where they live, work, play, and pray with health awareness and disease prevention messages and tools, screening programs, educational materials, advocacy opportunities, and patient navigation.

National Cancer Institute

1-800-4-CANCER
(1-800-422-6237)

Part of the National Institutes of Health, NCI is the nation’s leader in cancer research and training, providing information about prostate cancer as well as treatment options.

PCa BLUE

1-203-246-4882

PCa Blue is a nonprofit organization that has developed a national education and awareness program connecting blues music and musicians with the prostate cancer cause, presenting the important prostate cancer messages to men and their loved ones in the friendly and nonthreatening environment of a blues concert.

Patient Advocates for Advanced Cancer Treatments (PAACT) Inc.

1-616-453-1477

The PAACT organization is a nonprofit group dedicated to helping patients and caregivers develop a better understanding of their own cancer characteristics, empowering them to research more effectively and develop better questions for their medical team members.

Prostate Conditions Education Council (PCEC)

1-866-4PROST8
(1-866-477-6788)

PCEC is a national organization committed to men’s health that aims to conduct nationwide screenings for men and perform research to aid in the detection and treatment of prostate conditions.

Prostate Cancer Research Institute

1-800-641-PCRI
(1-800-641-7274)

The Prostate Cancer Research Institute’s mission is to improve the quality of prostate cancer patients’ and caregivers’ lives by supporting research and disseminating information that educates and empowers patients, families, and the medical community.

Prostate Health Education Network (PHEN)

1-617-481-4020

PHEN’s mission is to eliminate the African American prostate cancer disparity. Black men in the United States have the nation’s highest prostate cancer incidence and mortality rates. PHEN’s mission includes advocacy efforts to provide overall support and resources to wage a war on prostate cancer that will eventually lead to a cure for the disease for the benefit of all men.

Us TOO International prostate cancer education & Support

1-800-80-Us-TOO
(1-800-808-7866)

Us TOO is a prostate cancer education and support network dedicated to helping people take action against their disease and make informed decisions.

ZERO—The End of Prostate Cancer

1-202-463-9455

ZERO aims to create a collective voice for the prostate cancer movement by advancing research, encouraging action, and providing education and support to men and their families.

Indication

Xofigo (radium Ra 223 dichloride) injection is used to treat prostate cancer that is resistant to medical or surgical treatments that lower testosterone and has spread to your bones with symptoms, but not to other parts of your body. The medical term for this condition is metastatic castration-resistant prostate cancer, or mCRPC.

Important Safety Information

Do not take Xofigo if you are pregnant or may become pregnant. Xofigo can harm your unborn baby. Women who are pregnant or who may become pregnant should not come in contact with Xofigo without protection, such as gloves.

Before taking Xofigo, tell your healthcare provider if you:

  • have bone marrow problems. Xofigo can cause your blood cells counts to go down, including red blood cells, white blood cells, and/or platelets. In a clinical trial, some patients had to permanently discontinue therapy because of bone marrow problems. In addition, there were some deaths and blood transfusions that occurred due to severe bone marrow problems. Your healthcare provider will do blood tests before and during treatment with Xofigo
  • are receiving any chemotherapy or another extensive radiation therapy
  • have any other medical conditions

While you are on Xofigo:

  • make sure you keep your blood cell count monitoring appointments and tell your healthcare provider about any symptoms or signs of low blood cell counts. Report symptoms or signs of shortness of breath, tiredness, bleeding (such as bruising), or infection (such as fever)
  • stay well hydrated and report any signs of dehydration (such as dry mouth and increased thirst), or urinary or kidney problems (such as burning when urinating)
  • there are no restrictions regarding contact with other people after receiving Xofigo
  • follow good hygiene practices in order to minimize radiation exposure from spills of bodily fluids to household members and caregivers for a period of one week after each injection
  • use condoms and make sure female partners who may become pregnant use highly effective birth control methods during and for a minimum of six months after treatment with Xofigo

The most common side effects of Xofigo include:

  • nausea
  • diarrhea
  • vomiting
  • swelling of the arms or legs (peripheral edema)
  • low blood cell counts

Tell your healthcare provider if you have any side effects that bother you or do not go away.

For important risk and use information about Xofigo, please see the Full Prescribing Information.

You are encouraged to report negative side effects or quality complaints of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1‑800‑FDA‑1088.