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Important Safety Information

It is not known if Xofigo is safe and effective in women. Xofigo can harm unborn babies when given to a pregnant woman. Men should use condoms and make sure female partners who may become pregnant use birth control (contraception) during treatment and for 6 months after completing treatment with Xofigo.

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PATIENT VIDEOS

Your Video Guide to Xofigo

Watch this video to learn everything you need to know about Xofigo—from how it works to what to expect before, during, and after treatment.

Your Video Guide to Xofigo

YYMMDD Author/Uploaded by

Click here to see the full Prescribing Information for Xofigo.

Click here to see the full Prescribing Information for Xofigo.

Watch this video to learn everything you need to know about Xofigo—from how it works to what to expect before, during, and after treatment.

From Doctor to Patient

Practicing father-son urologists, Drs. Howard and Jonathan Schiff, found themselves on the other side of the desk when Dr. Howard Schiff was diagnosed with metastatic castration-resistant prostate cancerX metastatic castration-resistant prostate cancer
The medical term for when prostate cancer has spread to bone and the cancer is no longer responding to therapies aimed at lowering testosterone.
(mCRPCX mCRPC
The medical term for when prostate cancer has spread to bone and the cancer is no longer responding to therapies aimed at lowering testosterone.
). Being around for his family is the most important thing to Dr. Howard Schiff.

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YYMMDD Author/Uploaded by

Click here to see the full Prescribing Information for Xofigo.

Practicing father-son urologists, Drs. Howard and Jonathan Schiff, found themselves on the other side of the desk when Dr. Howard Schiff was diagnosed with metastatic castration-resistant prostate cancerX metastatic castration-resistant prostate cancer
The medical term for when prostate cancer has spread to bone and the cancer is no longer responding to therapies aimed at lowering testosterone.
(mCRPCX mCRPC
The medical term for when prostate cancer has spread to bone and the cancer is no longer responding to therapies aimed at lowering testosterone.
). Being around for his family is the most important thing to Dr. Howard Schiff.

Journey From Diagnosis to Treatment

Xofigo patient, Rick, and his wife share details about their experience with Rick's Xofigo treatment. From his initial diagnosis to the disease spreading to his bones, Rick and his wife remained committed to finding the right treatment for him.

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YYMMDD Author/Uploaded by

Click here to see the full Prescribing Information for Xofigo.

Xofigo patient, Rick, and his wife share details about their experience with Rick's Xofigo treatment. From his initial diagnosis to the disease spreading to his bones, Rick and his wife remained committed to finding the right treatment for him.

Be Your Own Healthcare Advocate

Dennis recommends learning all you can about prostate cancer that has spread to the bones and joining a support group.

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YYMMDD Author/Uploaded by

Click here to see the full Prescribing Information for Xofigo.

Dennis recommends learning all you can about prostate cancer that has spread to the bones and joining a support group.

Advice for Other Prostate Cancer Patients

Chuck, Bruce, and Charles discuss the role Xofigo played in their treatment and share their experience receiving Xofigo.

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YYMMDD Author/Uploaded by

Click here to see the full Prescribing Information for Xofigo.

Chuck, Bruce, and Charles discuss the role Xofigo played in their treatment and share their experience receiving Xofigo.

Life after diagnosis and treatment with Xofigo

After Richard's castration-resistant prostate cancer (CRPC) spread to the bone with symptoms, he found comfort and support from his family and wife Joanne. Hear about Richard's treatment journey, including his experience with Xofigo.

n/a

YYMMDD Author/Uploaded by

Click here to see the full Prescribing Information for Xofigo.

After Richard's castration-resistant prostate cancer (CRPC) spread to the bone with symptoms, he found comfort and support from his family and wife Joanne. Hear about Richard's treatment journey, including his experience with Xofigo.

 

Indication

Xofigo® (radium Ra 223 dichloride) injection is used to treat prostate cancer that no longer responds to hormonal or surgical treatment that lowers testosterone. It is for men whose prostate cancer has spread to the bone with symptoms but not to other parts of the body.

Important Safety Information

It is not known if Xofigo is safe and effective in women. Xofigo can harm unborn babies when given to a pregnant woman. Men should use condoms and make sure female partners who may become pregnant use birth control (contraception) during treatment and for 6 months after completing treatment with Xofigo.

Before taking Xofigo, tell your healthcare provider if you:

  • have bone marrow problems. Xofigo can cause your blood cells counts to go down, including red blood cells, white blood cells, and/or platelets. In a clinical trial, some patients had to permanently discontinue therapy because of bone marrow problems. In addition, there were some deaths and blood transfusions that occurred due to severe bone marrow problems. Your healthcare provider will do blood tests before and during treatment with Xofigo
  • are receiving any chemotherapy or another extensive radiation therapy
  • are taking Zytiga® (also known as abiraterone) with prednisone/prednisolone, as this may increase the risk of bone fractures (breaks) and death
  • have any other medical conditions

While you are on Xofigo:

  • make sure you keep your blood cell count monitoring appointments and tell your healthcare provider about any symptoms or signs of low blood cell counts. Report symptoms or signs of shortness of breath, tiredness, bleeding (such as bruising), or infection (such as fever)
  • stay well hydrated and report any signs of dehydration (such as dry mouth and increased thirst), or urinary or kidney problems (such as burning when urinating)
  • there are no restrictions regarding personal contact (visual or physical proximity) with other people after receiving Xofigo
  • people who are handling fluids such as urine, feces, or vomit of a man taking Xofigo should wear gloves and wash their hands as precaution
  • follow good hygiene practices in order to minimize radiation exposure from spills of bodily fluids to household members and caregivers for a period of one week after each injection

The most common side effects of Xofigo include:

  • nausea
  • diarrhea
  • vomiting
  • swelling of the arms or legs (peripheral edema)
  • low blood cell counts

Tell your healthcare provider if you have any side effects that bother you or do not go away.

For important risk and use information about Xofigo, please see the Full Prescribing Information.

You are encouraged to report side effects or quality complaints of products to the FDA by visiting www.fda.gov/medwatch, or call 1‑800‑FDA‑1088.